Comparing different types of statins for secondary prevention of cardio-cerebrovascular disease from a national cohort study

Statins have been recommended for use in atherosclerotic cardio-cerebrovascular disease (CCVD). The purpose of this study was to investigate the efficacy five different types statin secondary prevention CCVD patients. This retrospectively designed and analyzed data from National Health Insurance Service-National Korea. Participants aged 40 69 years were categorized into groups (atorvastatin, rosuvastatin, pitavastatin, simvastatin, pravastatin). primary composite outcome defined as recurrence or all causes death. Cox proportional hazard regression models adopted after stepwise adjustments confounders difference among statins. Of 755 final participants, 48 patients experienced outcomes. After adjustments, ratios (95% confidence intervals) outcomes atorvastatin, rosuvastatin 0.956 (0.456–2.005), 1.347 (0.354–5.116), 0.943 (0.317–2.803), respectively, when compared with simvastatin group. There no significant differences between statins preventing events and/or death